The Cardiovascular Effects of Metformin: Conventional and New Insights
نویسندگان
چکیده
Cite this article: Batchuluun B, Sonoda N, Takayanagi R, Inoguchi T (2014) The Cardiovascular Effects of Metformin: Conventional and New Insights. J Endocrinol Diabetes Obes 2(2): 1035. *Corresponding author Noriyuki Sonoda, Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan, Tel: +81-92-6425284; Fax: +81-92-642-5287; Email:
منابع مشابه
Fasting Reduces the Binding between Sugar and Protein; New Insights into Diabetic Complications
Fasting has numerous biological, physical and mental health advantages or that as some physicians cure their patients by prescribing fasting to them. Fasting protects people from many diseases such as cancer, cardiovascular diseases, and diabetes complications. The main health-promoting effects of fasting are increased production of neurotrophic factors, neuroendocrine activation, hormetic stre...
متن کاملComparative Effects of Metformin and Glibenclamide on Aortic Reactivity to Vasodilator and Vasoconstrictor Agents in STZ-Induced Diabetic Rats
Background: Diabetes is an important risk factor for cardiovascular events. Endothelial dysfunction is the main reason cause of disability and death in diabetic patients and death. The present study investigates the effects of metformin and glibenclamide on vasoconstrictive and vasodilative responses in the diabetic rat aorta. Methods: Rats were divided into four experimental groups (con...
متن کاملInsights into role of microRNAs in cardiac development, cardiac diseases, and developing novel therapies
Objective(s): MicroRNAs (miRNAs) are a subfamily of small noncoding RNAs that play a variety of roles in regulating gene expression in nearly all organisms. They affect different biological pathways by post-transcriptionally regulating mRNAs. Aside from miRNAs’ role in maintaining cellular homeostasis, their perturbation is related to several pathologic states and dis...
متن کاملSynergistic effects of metformin with liraglutide against endothelial dysfunction through GLP-1 receptor and PKA signalling pathway
Metformin or glucagon-like peptide-1 (GLP-1) analogue liraglutide has cardiovascular benefits. However, it is not clear whether their combined treatment have additive or synergistic effects on the vasculature. In this study, human umbilical vein endothelial cells (HUVECs), exposed to palmitic acid (PA) to induce endothelial dysfunction, were incubated with metformin, liraglutide or their combin...
متن کاملA Qualitative Study of Washback Effects of New Iranian TEFL Ph.D. Program Entrance Exam on Applicants’ Study Plans and Strategies: Insights From Instructors and Applicants
The newly administered Iranian Ph.D. Program Entrance Exam (PPEE) is supposed to have had different washback effects on university curriculums. This qualitative study examined the effects of the new TEFL PPEE on the applicants’ study plans and strategies from the points of view of both Iranian university instructors and applicants. To this end, we conducted in-depth interviews with 10 experienc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014